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Roles of Farnesyl-Diphosphate Farnesyltransferase 1 in Tumour and Tumour Microenvironments

Farnesyl-diphosphate farnesyltransferase 1 (FDFT1, squalene synthase), a membrane-associated enzyme, synthesizes squalene via condensation of two molecules of farnesyl pyrophosphate. Accumulating evidence has noted that FDFT1 plays a critical role in cancer, particularly in metabolic reprogramming,...

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Publicado en:Cells
Autores principales: Ha, Nguyen Thi, Lee, Chang Hoon
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7693003/
https://ncbi.nlm.nih.gov/pubmed/33113804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9112352
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