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Hybrid of Restricted and Penalized Maximum Likelihood Method for Efficient Genome-Wide Association Study
In genome-wide association studies, linear mixed models (LMMs) have been widely used to explore the molecular mechanism of complex traits. However, typical association approaches suffer from several important drawbacks: estimation of variance components in LMMs with large scale individuals is comput...
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| Publicado no: | Genes (Basel) |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7692801/ https://ncbi.nlm.nih.gov/pubmed/33138126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11111286 |
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