Non-Invasive Measurement of Drug and 2-HG Signals Using (19)F and (1)H MR Spectroscopy in Brain Tumors Treated with the Mutant IDH1 Inhibitor BAY1436032

SIMPLE SUMMARY: Targeted therapies are of growing interest to physicians in cancer treatment. These drugs target specific genes and proteins involved in the growth and survival of cancer cells. Brain tumor therapy is complicated by the fact that not all drugs can penetrate the blood brain barrier an...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Wenger, Katharina J., Richter, Christian, Burger, Michael C., Urban, Hans, Kaulfuss, Stefan, Harter, Patrick N., Sreeramulu, Sridhar, Schwalbe, Harald, Steinbach, Joachim P., Hattingen, Elke, Bähr, Oliver, Pilatus, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7692790/
https://ncbi.nlm.nih.gov/pubmed/33138036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12113175
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