Llwytho...
P07.06 Does IDH1 R132H Mutation alter phospholipid metabolism in glioma? A 31 P-MRS in vivo study
PURPOSE: IDH1 mutations have been identified in approximately 70–80% of cases of diffuse glioma (grades II-III) and secondary glioblastoma multiforme (grade IV). The mutation in IDH1 confers a gain of function neomorphic activity to the enzyme, which results in NADPH-dependent conversion of α-Ketogl...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Neuro Oncol |
|---|---|
| Prif Awduron: | , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Oxford University Press
2016
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5782614/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now188.117 |
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