Liver Ischemia Reperfusion Injury, Enhanced by Trained Immunity, Is Attenuated in Caspase 1/Caspase 11 Double Gene Knockout Mice

Ischemia reperfusion injury (IRI) during liver transplantation increases morbidity and contributes to allograft dysfunction. There are no therapeutic strategies to mitigate IRI. We examined a novel hypothesis: caspase 1 and caspase 11 serve as danger-associated molecular pattern (DAMPs) sensors in I...

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Xehetasun bibliografikoak
Argitaratua izan da:Pathogens
Egile Nagusiak: Fagenson, Alexander M., Xu, Keman, Saaoud, Fatma, Nanayakkara, Gayani, Jhala, Nirag C., Liu, Lu, Drummer, Charles, Sun, Yu, Lau, Kwan N., Di Carlo, Antonio, Jiang, Xiaohua, Wang, Hong, Karhadkar, Sunil S., Yang, Xiaofeng
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7692674/
https://ncbi.nlm.nih.gov/pubmed/33114395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pathogens9110879
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