Rab11A Functions as a Negative Regulator of Osteoclastogenesis through Dictating Lysosome-Induced Proteolysis of c-fms and RANK Surface Receptors

Osteoclast differentiation and activity are controlled by two essential cytokines, macrophage colony-stimulating factor (M-CSF) and the receptor activator of nuclear factor-κB ligand (RANKL). Rab11A GTPase, belonging to Rab11 subfamily representing the largest branch of Ras superfamily of small GTPa...

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Bibliografiske detaljer
Udgivet i:	Cells
Main Authors:	Okusha, Yuka, Tran, Manh Tien, Itagaki, Mami, Sogawa, Chiharu, Eguchi, Takanori, Okui, Tatsuo, Kadowaki, Tomoko, Sakai, Eiko, Tsukuba, Takayuki, Okamoto, Kuniaki
Format:	Artigo
Sprog:	Inglês
Udgivet:	MDPI 2020
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC7692573/ https://ncbi.nlm.nih.gov/pubmed/33142674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9112384
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Rab11A Functions as a Negative Regulator of Osteoclastogenesis through Dictating Lysosome-Induced Proteolysis of c-fms and RANK Surface Receptors

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