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A Review of the Important Role of CYP2D6 in Pharmacogenomics

Cytochrome P450 2D6 (CYP2D6) is a critical pharmacogene involved in the metabolism of ~20% of commonly used drugs across a broad spectrum of medical disciplines including psychiatry, pain management, oncology and cardiology. Nevertheless, CYP2D6 is highly polymorphic with single-nucleotide polymorph...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Taylor, Christopher, Crosby, Ian, Yip, Vincent, Maguire, Peter, Pirmohamed, Munir, Turner, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7692531/
https://ncbi.nlm.nih.gov/pubmed/33143137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11111295
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