A Molecular Test for Quantifying Functional Notch Signaling Pathway Activity in Human Cancer

SIMPLE SUMMARY: The Notch signal transduction pathway is important for various physiological processes, including immune responses, and plays a role in many diseases, for example cancer. We have developed a new assay to quantitatively measure Notch pathway activity, and we validated it using data fr...

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Bibliografiske detaljer
Udgivet i:Cancers (Basel)
Main Authors: Canté-Barrett, Kirsten, Holtzer, Laurent, van Ooijen, Henk, Hagelaar, Rico, Cordo’, Valentina, Verhaegh, Wim, van de Stolpe, Anja, Meijerink, Jules P. P.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7692325/
https://ncbi.nlm.nih.gov/pubmed/33120947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12113142
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