Proinflammatory Cytokine Interleukin 1β Disrupts β-cell Circadian Clock Function and Regulation of Insulin Secretion

Intrinsic β-cell circadian clocks are important regulators of insulin secretion and overall glucose homeostasis. Whether the circadian clock in β-cells is perturbed following exposure to prodiabetogenic stressors such as proinflammatory cytokines, and whether these perturbations are featured during...

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Bibliographic Details
Published in:Endocrinology
Main Authors: Javeed, Naureen, Brown, Matthew R, Rakshit, Kuntol, Her, Tracy, Sen, Satish K, Matveyenko, Aleksey V
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7692023/
https://ncbi.nlm.nih.gov/pubmed/32455427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/endocr/bqaa084
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