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Circadian Disruption and Diet-Induced Obesity Synergize to Promote Development of β-Cell Failure and Diabetes in Male Rats

There are clear epidemiological associations between circadian disruption, obesity, and pathogenesis of type 2 diabetes. The mechanisms driving these associations are unclear. In the current study, we hypothesized that continuous exposure to constant light (LL) compromises pancreatic β-cell function...

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Dettagli Bibliografici
Pubblicato in:Endocrinology
Autori principali: Qian, Jingyi, Yeh, Bonnie, Rakshit, Kuntol, Colwell, Christopher S., Matveyenko, Aleksey V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4655211/
https://ncbi.nlm.nih.gov/pubmed/26348474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-1516
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