Circadian Disruption and Diet-Induced Obesity Synergize to Promote Development of β-Cell Failure and Diabetes in Male Rats

There are clear epidemiological associations between circadian disruption, obesity, and pathogenesis of type 2 diabetes. The mechanisms driving these associations are unclear. In the current study, we hypothesized that continuous exposure to constant light (LL) compromises pancreatic β-cell function...

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Bibliographic Details
Published in:Endocrinology
Main Authors: Qian, Jingyi, Yeh, Bonnie, Rakshit, Kuntol, Colwell, Christopher S., Matveyenko, Aleksey V.
Format: Artigo
Language:Inglês
Published: Endocrine Society 2015
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4655211/
https://ncbi.nlm.nih.gov/pubmed/26348474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-1516
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