A stem cell reporter based platform to identify and target drug resistant stem cells in myeloid leukemia

Intratumoral heterogeneity is a common feature of many myeloid leukemias and a significant reason for treatment failure and relapse. Thus, identifying the cells responsible for residual disease and leukemia re-growth is critical to better understanding how they are regulated. Here, we show that a kn...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Spinler, Kyle, Bajaj, Jeevisha, Ito, Takahiro, Zimdahl, Bryan, Hamilton, Michael, Ahmadi, Armin, Koechlein, Claire S., Lytle, Nikki, Kwon, Hyog Young, Anower-E-Khuda, Ferdous, Sun, Hao, Blevins, Allen, Weeks, Joi, Kritzik, Marcie, Karlseder, Jan, Ginsberg, Mark H., Park, Pyong Woo, Esko, Jeffrey D., Reya, Tannishtha
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7691523/
https://ncbi.nlm.nih.gov/pubmed/33243988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19782-x
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