β-arrestin 2 as an activator of cGAS-STING signaling and target of viral immune evasion

Virus infection may induce excessive interferon (IFN) responses that can lead to host tissue injury or even death. β-arrestin 2 regulates multiple cellular events through the G protein-coupled receptor (GPCR) signaling pathways. Here we demonstrate that β-arrestin 2 also promotes virus-induced produ...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Zhang, Yihua, Li, Manman, Li, Liuyan, Qian, Gui, Wang, Yu, Chen, Zijuan, Liu, Jing, Fang, Chao, Huang, Feng, Guo, Daqiao, Zou, Quanming, Chu, Yiwei, Yan, Dapeng
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7691508/
https://ncbi.nlm.nih.gov/pubmed/33243993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19849-9
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