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Conserved strategies for pathogen evasion of cGAS–STING immunity

The cyclic GMP–AMP synthase (cGAS)– Stimulator of Interferon Genes (STING) pathway of cytosolic DNA sensing allows mammalian cells to detect and respond to infection with diverse pathogens. Pathogens in turn encode numerous factors that inhibit nearly all steps of cGAS–STING signal transduction. Fro...

詳細記述

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書誌詳細
出版年:Curr Opin Immunol
主要な著者: Eaglesham, James B, Kranzusch, Philip J
フォーマット: Artigo
言語:Inglês
出版事項: The Author(s). Published by Elsevier Ltd. 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7158794/
https://ncbi.nlm.nih.gov/pubmed/32339908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2020.04.002
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