Bacterial OTU deubiquitinases regulate substrate ubiquitination upon Legionella infection

Legionella pneumophila causes a severe pneumonia known as Legionnaires’ disease. During the infection, Legionella injects more than 300 effector proteins into host cells. Among them are enzymes involved in altering the host-ubiquitination system. Here, we identified two LegionellaOTU (ovarian tumor)...

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Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Shin, Donghyuk, Bhattacharya, Anshu, Cheng, Yi-Lin, Alonso, Marta Campos, Mehdipour, Ahmad Reza, van der Heden van Noort, Gerbrand J, Ovaa, Huib, Hummer, Gerhard, Dikic, Ivan
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2020
Fag:
Biochemistry and Chemical Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7690952/
https://ncbi.nlm.nih.gov/pubmed/33185526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.58277
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