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Regioselective Hydroxylation of Phloretin, a Bioactive Compound from Apples, by Human Cytochrome P450 Enzymes

Phloretin, the major polyphenol compound in apples and apple products, is interesting because it shows beneficial effects on human health. It is mainly found as a form of glucoside, phlorizin. However, the metabolic pathway of phloretin in humans has not been reported. Therefore, identifying phloret...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: Nguyen, Ngoc Anh, Cao, Ngoc Tan, Nguyen, Thi Huong Ha, Le, Thien-Kim, Cha, Gun Su, Choi, Soo-Keun, Pan, Jae-Gu, Yeom, Soo-Jin, Kang, Hyung-Sik, Yun, Chul-Ho
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7690628/
https://ncbi.nlm.nih.gov/pubmed/33105851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph13110330
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