Macrophage to myofibroblast transition contributes to subretinal fibrosis secondary to neovascular age-related macular degeneration

BACKGROUND: Macular fibrosis causes irreparable vision loss in neovascular age-related macular degeneration (nAMD) even with anti-vascular endothelial growth factor (VEGF) therapy. Inflammation is known to play an important role in macular fibrosis although the underlying mechanism remains poorly de...

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Bibliografiske detaljer
Udgivet i:J Neuroinflammation
Main Authors: Little, Karis, Llorián-Salvador, Maria, Tang, Miao, Du, Xuan, Marry, Stephen, Chen, Mei, Xu, Heping
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7690191/
https://ncbi.nlm.nih.gov/pubmed/33239022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-02033-7
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