A Two-Stage Laser-Induced Mouse Model of Subretinal Fibrosis Secondary to Choroidal Neovascularization

PURPOSE: To develop a model that can recapitulate key features of macular fibrosis in neovascular age-related macular degeneration (nAMD). METHODS: Adult C57BL/6J mice received three laser burns/eye to induce choroidal neovascularization (CNV). Seven days later, a second laser burn was directed to e...

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Udgivet i:Transl Vis Sci Technol
Main Authors: Little, Karis, Llorián-Salvador, María, Tang, Miao, Du, Xuan, O'Shaughnessy, Órlaith, McIlwaine, Gemma, Chen, Mei, Xu, Heping
Format: Artigo
Sprog:Inglês
Udgivet: The Association for Research in Vision and Ophthalmology 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7396176/
https://ncbi.nlm.nih.gov/pubmed/32818091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/tvst.9.4.3
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