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Reversal of Regioselectivity in Zinc‐Dependent Medium‐Chain Alcohol Dehydrogenase from Rhodococcus erythropolis toward Octanone Derivatives

The zinc‐dependent medium‐chain alcohol dehydrogenase from Rhodococcus erythropolis (ReADH) is one of the most versatile biocatalysts for the stereoselective reduction of ketones to chiral alcohols. Despite its known broad substrate scope, ReADH only accepts carbonyl substrates with either a methyl...

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Dettagli Bibliografici
Pubblicato in:Chembiochem
Autori principali: Dhoke, Gaurao V., Ensari, Yunus, Hacibaloglu, Dinc Yasat, Gärtner, Anna, Ruff, Anna Joëlle, Bocola, Marco, Davari, Mehdi D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7689849/
https://ncbi.nlm.nih.gov/pubmed/32415803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.202000247
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