Reversal of Regioselectivity in Zinc‐Dependent Medium‐Chain Alcohol Dehydrogenase from Rhodococcus erythropolis toward Octanone Derivatives

The zinc‐dependent medium‐chain alcohol dehydrogenase from Rhodococcus erythropolis (ReADH) is one of the most versatile biocatalysts for the stereoselective reduction of ketones to chiral alcohols. Despite its known broad substrate scope, ReADH only accepts carbonyl substrates with either a methyl...

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Bibliografische gegevens
Gepubliceerd in:Chembiochem
Hoofdauteurs: Dhoke, Gaurao V., Ensari, Yunus, Hacibaloglu, Dinc Yasat, Gärtner, Anna, Ruff, Anna Joëlle, Bocola, Marco, Davari, Mehdi D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2020
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Full Papers
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7689849/
https://ncbi.nlm.nih.gov/pubmed/32415803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.202000247
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