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Relationship Between Progression‐Free Survival, Objective Response Rate, and Overall Survival in Clinical Trials of PD‐1/PD‐L1 Immune Checkpoint Blockade: A Meta‐Analysis

PD‐1/PD‐L1 immune checkpoint blockade (ICB) has improved overall survival (OS) in solid tumor trials; however, parallel improvements in Response Evaluation Criteria in Solid Tumors (RECIST)‐based surrogate end points, progression‐free survival (PFS), and objective response rate (ORR), are not always...

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Detalhes bibliográficos
Publicado no:Clin Pharmacol Ther
Main Authors: Ye, Jiabu, Ji, Xiang, Dennis, Phillip A., Abdullah, Hesham, Mukhopadhyay, Pralay
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7689755/
https://ncbi.nlm.nih.gov/pubmed/32564368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.1956
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