Pipoxolan suppresses the inflammatory factors of NF‐κB, AP‐1, and STATs, but activates the antioxidative factor Nrf2 in LPS‐stimulated RAW 264.7 murine macrophage cells

Although pipoxolan (PIPO) is a smooth muscle relaxant, its anti‐inflammatory capability has not been studied. Therefore, we investigated the anti‐inflammatory molecular mechanisms of PIPO in lipopolysaccharide (LPS)‐induced RAW 264.7 macrophages. In this study, we used the MTT assay to evaluate the...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Environ Toxicol
Prif Awduron: Lin, Yu‐Hsien, Lin, Yu‐Jung, Chang, Ting‐Hsuan, Chang, Yun‐Hsuan, Lim, Yun‐Ping, Chung, Jing‐Gung, Hsieh, Wen‐Tsong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley & Sons, Inc. 2020
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7689704/
https://ncbi.nlm.nih.gov/pubmed/32677756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/tox.23000
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