Pipoxolan suppresses the inflammatory factors of NF‐κB, AP‐1, and STATs, but activates the antioxidative factor Nrf2 in LPS‐stimulated RAW 264.7 murine macrophage cells

Although pipoxolan (PIPO) is a smooth muscle relaxant, its anti‐inflammatory capability has not been studied. Therefore, we investigated the anti‐inflammatory molecular mechanisms of PIPO in lipopolysaccharide (LPS)‐induced RAW 264.7 macrophages. In this study, we used the MTT assay to evaluate the...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Environ Toxicol
Main Authors: Lin, Yu‐Hsien, Lin, Yu‐Jung, Chang, Ting‐Hsuan, Chang, Yun‐Hsuan, Lim, Yun‐Ping, Chung, Jing‐Gung, Hsieh, Wen‐Tsong
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons, Inc. 2020
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7689704/
https://ncbi.nlm.nih.gov/pubmed/32677756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/tox.23000
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