Defects in DNA Repair Genes Confer Improved Long-term Survival after Cisplatin-based Neoadjuvant Chemotherapy for Muscle Invasive Bladder Cancer

Cisplatin-based neoadjuvant chemotherapy (NAC) has demonstrated an overall survival (OS) benefit in muscle invasive bladder cancer (MIBC). However, only a subset of patients (25–50%) have pathologic complete response at cystectomy. Using a cohort of patients (n = 58) from two phase II trials, our gr...

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Publicado en:Eur Urol Oncol
Autores principales: Miron, Benjamin, Hoffman-Censits, Jean H., Anari, Fern, O’Neill, John, Geynisman, Daniel M., Zibelman, Matthew R., Kutikov, Alexander, Viterbo, Rosalia, Greenberg, Richard E., Chen, David, Lallas, Costas D., Trabulsi, Edouard John, Alpaugh, R. Katherine, Dulaimi, Essel, Golemis, Erica A., Uzzo, Robert, Ross, Eric A., Plimack, Elizabeth R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7689684/
https://ncbi.nlm.nih.gov/pubmed/32165095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.euo.2020.02.003
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