Defects in DNA Repair Genes Confer Improved Long-term Survival after Cisplatin-based Neoadjuvant Chemotherapy for Muscle Invasive Bladder Cancer

Cisplatin-based neoadjuvant chemotherapy (NAC) has demonstrated an overall survival (OS) benefit in muscle invasive bladder cancer (MIBC). However, only a subset of patients (25–50%) have pathologic complete response at cystectomy. Using a cohort of patients (n = 58) from two phase II trials, our gr...

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Detalhes bibliográficos
Publicado no:Eur Urol Oncol
Main Authors: Miron, Benjamin, Hoffman-Censits, Jean H., Anari, Fern, O’Neill, John, Geynisman, Daniel M., Zibelman, Matthew R., Kutikov, Alexander, Viterbo, Rosalia, Greenberg, Richard E., Chen, David, Lallas, Costas D., Trabulsi, Edouard John, Alpaugh, R. Katherine, Dulaimi, Essel, Golemis, Erica A., Uzzo, Robert, Ross, Eric A., Plimack, Elizabeth R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7689684/
https://ncbi.nlm.nih.gov/pubmed/32165095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.euo.2020.02.003
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