Genetic determinants of increased body mass index mediate the effect of smoking on increased risk for type 2 diabetes but not coronary artery disease

Clinical observations have linked tobacco smoking with increased type 2 diabetes risk. Mendelian randomization analysis has recently suggested smoking may be a causal risk factor for type 2 diabetes. However, this association could be mediated by additional risk factors correlated with smoking behav...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Hum Mol Genet
Päätekijät: Thom, Christopher S, Ding, Zhuoran, Levin, Michael G, Damrauer, Scott M, Lee, Kyung Min, Lynch, Julie, Chang, Kyong-Mi, Tsao, Philip S, Cho, Kelly, Wilson, Peter W F, Assimes, Themistocles L, Sun, Yan V, O’Donnell, Christopher J, Vujkovic, Marijana, Voight, Benjamin F
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2020
Aiheet:
Association Studies Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7689293/
https://ncbi.nlm.nih.gov/pubmed/32833022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddaa193
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