Association between Genetic Variation in Blood Pressure and Increased Lifetime Risk of Peripheral Artery Disease

AIMS: We aimed to estimate the effect of blood pressure (BP) traits and BP-lowering medications (via genetic proxies) on peripheral artery disease. METHODS AND RESULTS: GWAS summary statistics were obtained for BP, peripheral artery disease (PAD), and coronary artery disease (CAD). Causal effects of...

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Pubblicato in:Arterioscler Thromb Vasc Biol
Autori principali: Levin, Michael G., Klarin, Derek, Walker, Venexia M., Gill, Dipender, Lynch, Julie, Hellwege, Jacklyn N., Keaton, Jacob M., Lee, Kyung M., Assimes, Themistocles L., Natarajan, Pradeep, Hung, Adriana M., Edwards, Todd, Rader, Daniel J., Gaziano, J. Michael, Davies, Neil M., Tsao, Philip S., Chang, Kyong-Mi, Voight, Benjamin F., Damrauer, Scott M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8159880/
https://ncbi.nlm.nih.gov/pubmed/33853351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.120.315482
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