Signature-based approaches for informed drug repurposing: targeting CNS disorders

CNS disorders, and in particular psychiatric illnesses, lack definitive disease-altering therapeutics. The limited understanding of the mechanisms driving these illnesses with the slow pace and high cost of drug development exacerbates this issue. For these reasons, drug repurposing – both a less ex...

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Veröffentlicht in:Neuropsychopharmacology
Hauptverfasser: Shukla, Rammohan, Henkel, Nicholas D., Alganem, Khaled, Hamoud, Abdul-rizaq, Reigle, James, Alnafisah, Rawan S., Eby, Hunter M., Imami, Ali S., Creeden, Justin F, Miruzzi, Scott A., Meller, Jaroslaw, Mccullumsmith, Robert E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer International Publishing 2020
Schlagworte:
Neuropsychopharmacology Reviews
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7688959/
https://ncbi.nlm.nih.gov/pubmed/32604402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-020-0752-6
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