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S183. ABNORMALITIES IN SERINE/THREONINE SIGNALING NETWORKS IN SEVERE NEUROPSYCHIATRIC ILLNESS: DEVELOPMENT OF A PIPELINE TO EXPLORE ABNORMALITIES OF KINASE ACTIVITY AND IDENTIFY NOVEL TREATMENT STRATEGIES FOR SCHIZOPHRENIA

BACKGROUND: Abnormalities of cellular signaling are well characterized in neuropsychiatric illnesses, including schizophrenia. Changes in signaling pathways reflect the underlying genetic, environmental, and epigenetic perturbations driving disease phenotypes. A shortcoming of most signaling studies...

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Detalhes bibliográficos
Publicado no:Schizophr Bull
Main Authors: McCullumsmith, Robert, Alganem, Khaled, Henkel, Nicholas, Hammoud, Abdul, Shukla, Rammohan, Ramsey, Amy, Wu, Wilma, Meller, Jarek
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7234751/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbaa031.249
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