Towards integration of (64)Cu-DOTA-trastuzumab PET-CT and MRI with mathematical modeling to predict response to neoadjuvant therapy in HER2 + breast cancer

While targeted therapies exist for human epidermal growth factor receptor 2 positive (HER2 +) breast cancer, HER2 + patients do not always respond to therapy. We present the results of utilizing a biophysical mathematical model to predict tumor response for two HER2 + breast cancer patients treated...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Jarrett, Angela M., Hormuth, David A., Adhikarla, Vikram, Sahoo, Prativa, Abler, Daniel, Tumyan, Lusine, Schmolze, Daniel, Mortimer, Joanne, Rockne, Russell C., Yankeelov, Thomas E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7688955/
https://ncbi.nlm.nih.gov/pubmed/33239688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77397-0
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