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The H741D mutation in Tac1p contributes to the upregulation of CDR1 and CDR2 expression in Candida albicans

The wide use of antifungal agents has led to the development of resistance in the pathogenic yeast strain Candida albicans. Gain-of-function mutations in transcription factors such as Tac1p demonstrated their ability to control expression of the ABC transporter genes CDR1 and CDR2, and mediation of...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Braz J Microbiol
Main Authors: Liu, Jin-Yan, Wei, Bing, Wang, Ying, Shi, Ce, Li, Wen-Jing, Zhao, Yue, Meng, Ling-Ning, Xiang, Ming-Jie
Format: Artigo
Jezik:Inglês
Izdano: Springer International Publishing 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7688751/
https://ncbi.nlm.nih.gov/pubmed/32648240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s42770-020-00336-8
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