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The H741D mutation in Tac1p contributes to the upregulation of CDR1 and CDR2 expression in Candida albicans
The wide use of antifungal agents has led to the development of resistance in the pathogenic yeast strain Candida albicans. Gain-of-function mutations in transcription factors such as Tac1p demonstrated their ability to control expression of the ABC transporter genes CDR1 and CDR2, and mediation of...
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| Publicado no: | Braz J Microbiol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer International Publishing
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7688751/ https://ncbi.nlm.nih.gov/pubmed/32648240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s42770-020-00336-8 |
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