Proteomic analysis of young and old mouse hematopoietic stem cells and their progenitors reveals post-transcriptional regulation in stem cells

The balance of hematopoietic stem cell (HSC) self-renewal and differentiation is critical for a healthy blood supply; imbalances underlie hematological diseases. The importance of HSCs and their progenitors have led to their extensive characterization at genomic and transcriptomic levels. However, t...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Zaro, Balyn W, Noh, Joseph J, Mascetti, Victoria L, Demeter, Janos, George, Benson, Zukowska, Monika, Gulati, Gunsagar S, Sinha, Rahul, Flynn, Ryan A, Banuelos, Allison, Zhang, Allison, Wilkinson, Adam C, Jackson, Peter, Weissman, Irving L
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Stem Cells and Regenerative Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7688314/
https://ncbi.nlm.nih.gov/pubmed/33236985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.62210
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