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Improved production of SARS-CoV-2 spike receptor-binding domain (RBD) for serology assays

The receptor-binding domain (RBD) of the SARS-CoV-2 spike protein is a commonly used antigen for serology assays critical to determining the extent of SARS-CoV-2 exposure in the population. Different versions of the RBD protein have been developed and utilized in assays, with higher sensitivity attr...

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Bibliographic Details
Published in:Protein Expr Purif
Main Authors: Mehalko, Jennifer, Drew, Matthew, Snead, Kelly, Denson, John-Paul, Wall, Vanessa, Taylor, Troy, Sadtler, Kaitlyn, Messing, Simon, Gillette, William, Esposito, Dominic
Format: Artigo
Language:Inglês
Published: Elsevier Inc. 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7687410/
https://ncbi.nlm.nih.gov/pubmed/33248226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pep.2020.105802
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