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Optimizing high-yield production of SARS-CoV-2 soluble spike trimers for serology assays
The SARS-CoV-2 spike trimer is the primary antigen for several serology assays critical to determining the extent of SARS-CoV-2 exposure in the population. Until stable cell lines are developed to increase the titer of this secreted protein in mammalian cell culture, the low yield of spike protein p...
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| Опубликовано в: : | Protein Expr Purif |
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| Главные авторы: | , , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Elsevier Inc.
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7271859/ https://ncbi.nlm.nih.gov/pubmed/32504802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pep.2020.105686 |
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