Mucosal concentrations of N‐acetyl‐5‐aminosalicylic acid related to endoscopic activity in ulcerative colitis patients with mesalamine

BACKGROUND AND AIM: 5‐Aminosalicylic acid (5‐ASA) is a fundamental treatment for mild‐to‐moderate ulcerative colitis (UC). 5‐ASA is taken up into the colonic mucosa and metabolized to N‐acetyl‐5‐ASA (Ac‐5‐ASA). Few studies have assessed whether mucosal 5‐ASA and Ac‐5‐ASA concentrations are associate...

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Dades bibliogràfiques
Publicat a:J Gastroenterol Hepatol
Autors principals: Fukuda, Tomohiro, Naganuma, Makoto, Takabayashi, Kaoru, Hagihara, Yuya, Tanemoto, Shun, Nomura, Ena, Yoshimatsu, Yusuke, Sugimoto, Shinya, Nanki, Kosaku, Mizuno, Shinta, Mikami, Yohei, Fukuhara, Kayoko, Sujino, Tomohisa, Mutaguchi, Makoto, Inoue, Nagamu, Ogata, Haruhiko, Iwao, Yasushi, Abe, Takayuki, Kanai, Takanori
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Clinical Gastroenterology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7687243/
https://ncbi.nlm.nih.gov/pubmed/32250471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jgh.15059
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