Mucosal concentrations of N‐acetyl‐5‐aminosalicylic acid related to endoscopic activity in ulcerative colitis patients with mesalamine

BACKGROUND AND AIM: 5‐Aminosalicylic acid (5‐ASA) is a fundamental treatment for mild‐to‐moderate ulcerative colitis (UC). 5‐ASA is taken up into the colonic mucosa and metabolized to N‐acetyl‐5‐ASA (Ac‐5‐ASA). Few studies have assessed whether mucosal 5‐ASA and Ac‐5‐ASA concentrations are associate...

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Detalhes bibliográficos
Publicado no:J Gastroenterol Hepatol
Main Authors: Fukuda, Tomohiro, Naganuma, Makoto, Takabayashi, Kaoru, Hagihara, Yuya, Tanemoto, Shun, Nomura, Ena, Yoshimatsu, Yusuke, Sugimoto, Shinya, Nanki, Kosaku, Mizuno, Shinta, Mikami, Yohei, Fukuhara, Kayoko, Sujino, Tomohisa, Mutaguchi, Makoto, Inoue, Nagamu, Ogata, Haruhiko, Iwao, Yasushi, Abe, Takayuki, Kanai, Takanori
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Clinical Gastroenterology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7687243/
https://ncbi.nlm.nih.gov/pubmed/32250471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jgh.15059
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