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Ferroptosis Mediates Cuprizone-Induced Loss of Oligodendrocytes and Demyelination

Multiple sclerosis (MS) is a chronic demyelinating disease of the CNS. Cuprizone (CZ), a copper chelator, is widely used to study demyelination and remyelination in the CNS, in the context of MS. However, the mechanisms underlying oligodendrocyte (OL) cell loss and demyelination are not known. As co...

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Bibliografski detalji
Izdano u:J Neurosci
Glavni autori: Jhelum, Priya, Santos-Nogueira, Eva, Teo, Wulin, Haumont, Alice, Lenoël, Isadora, Stys, Peter K., David, Samuel
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7687057/
https://ncbi.nlm.nih.gov/pubmed/33106352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1749-20.2020
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