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Ferroptosis Mediates Cuprizone-Induced Loss of Oligodendrocytes and Demyelination
Multiple sclerosis (MS) is a chronic demyelinating disease of the CNS. Cuprizone (CZ), a copper chelator, is widely used to study demyelination and remyelination in the CNS, in the context of MS. However, the mechanisms underlying oligodendrocyte (OL) cell loss and demyelination are not known. As co...
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| Pubblicato in: | J Neurosci |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Society for Neuroscience
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7687057/ https://ncbi.nlm.nih.gov/pubmed/33106352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1749-20.2020 |
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