Ferroptosis Mediates Cuprizone-Induced Loss of Oligodendrocytes and Demyelination

Multiple sclerosis (MS) is a chronic demyelinating disease of the CNS. Cuprizone (CZ), a copper chelator, is widely used to study demyelination and remyelination in the CNS, in the context of MS. However, the mechanisms underlying oligodendrocyte (OL) cell loss and demyelination are not known. As co...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Jhelum, Priya, Santos-Nogueira, Eva, Teo, Wulin, Haumont, Alice, Lenoël, Isadora, Stys, Peter K., David, Samuel
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7687057/
https://ncbi.nlm.nih.gov/pubmed/33106352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1749-20.2020
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