βOHB Protective Pathways in Aralar-KO Neurons and Brain: An Alternative to Ketogenic Diet

Aralar/AGC1/Slc25a12, the mitochondrial aspartate-glutamate carrier expressed in neurons, is the regulatory component of the NADH malate-aspartate shuttle. AGC1 deficiency is a neuropediatric rare disease characterized by hypomyelination, hypotonia, developmental arrest, and epilepsy. We have invest...

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Vydáno v:J Neurosci
Hlavní autoři: Pérez-Liébana, Irene, Casarejos, María José, Alcaide, Andrea, Herrada-Soler, Eduardo, Llorente-Folch, Irene, Contreras, Laura, Satrústegui, Jorgina, Pardo, Beatriz
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2020
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Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7687055/
https://ncbi.nlm.nih.gov/pubmed/33087477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0711-20.2020
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