Molecular Engineering of Ultrasmall Silica Nanoparticle-Drug Conjugates as Lung Cancer Therapeutics

PURPOSE: Small molecule inhibitors have had a major impact on cancer care. While treatments have demonstrated clinically promising results, they suffer from dose-limiting toxicities and the emergence of refractory disease. Considerable efforts made to address these issues have more recently focused...

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Gepubliceerd in:Clin Cancer Res
Hoofdauteurs: Madajewski, Brian, Chen, Feng, Yoo, Barney, Turker, Melik Z., Ma, Kai, Zhang, Li, Chen, Pei-Ming, Juthani, Rupa, Aragon-Sanabria, Virginia, Gonen, Mithat, Rudin, Charles M., Wiesner, Ulrich, Bradbury, Michelle S., Brennan, Cameron
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686858/
https://ncbi.nlm.nih.gov/pubmed/32723835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-20-0851
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