Dose- and time-dependent effects of hyaluronidase on structural cells and the extracellular matrix of the skin

INTRODUCTION: Hyaluronic acid (hyaluronan; HA) is an essential component of the extracellular matrix (ECM) of the skin. The HA-degrading enzyme hyaluronidase (HYAL) is critically involved in the HA-metabolism. Yet, only little information is available regarding the skin’s HA–HYAL interactions on the...

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Publicat a:Eur J Med Res
Autors principals: Buhren, Bettina Alexandra, Schrumpf, Holger, Gorges, Katharina, Reiners, Oliver, Bölke, Edwin, Fischer, Jens W., Homey, Bernhard, Gerber, Peter Arne
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686775/
https://ncbi.nlm.nih.gov/pubmed/33228813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40001-020-00460-z
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