Ingenol mebutate induces a tumor cell-directed inflammatory response and antimicrobial peptides thereby promoting rapid tumor destruction and wound healing

BACKGROUND: Ingenol mebutat (IM)-gel is effective for the topical treatment of epithelial tumors, including actinic keratoses (AKs) or anogenital warts (AGW). AK patients treated with IM develop intensified inflammatory reactions on sights of prior clinical visible or palpable AKs as compared to the...

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Detalhes bibliográficos
Publicado no:Eur J Med Res
Main Authors: Braun, Stephan Alexander, Baran, Julia, Schrumpf, Holger, Buhren, Bettina Alexandra, Bölke, Edwin, Homey, Bernhard, Gerber, Peter Arne
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6161468/
https://ncbi.nlm.nih.gov/pubmed/30266096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40001-018-0343-8
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