Ingenol mebutate induces a tumor cell-directed inflammatory response and antimicrobial peptides thereby promoting rapid tumor destruction and wound healing

BACKGROUND: Ingenol mebutat (IM)-gel is effective for the topical treatment of epithelial tumors, including actinic keratoses (AKs) or anogenital warts (AGW). AK patients treated with IM develop intensified inflammatory reactions on sights of prior clinical visible or palpable AKs as compared to the...

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Dettagli Bibliografici
Pubblicato in:Eur J Med Res
Autori principali: Braun, Stephan Alexander, Baran, Julia, Schrumpf, Holger, Buhren, Bettina Alexandra, Bölke, Edwin, Homey, Bernhard, Gerber, Peter Arne
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6161468/
https://ncbi.nlm.nih.gov/pubmed/30266096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40001-018-0343-8
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