Ingenol mebutate induces a tumor cell-directed inflammatory response and antimicrobial peptides thereby promoting rapid tumor destruction and wound healing

BACKGROUND: Ingenol mebutat (IM)-gel is effective for the topical treatment of epithelial tumors, including actinic keratoses (AKs) or anogenital warts (AGW). AK patients treated with IM develop intensified inflammatory reactions on sights of prior clinical visible or palpable AKs as compared to the...

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Библиографические подробности
Опубликовано в: :Eur J Med Res
Главные авторы: Braun, Stephan Alexander, Baran, Julia, Schrumpf, Holger, Buhren, Bettina Alexandra, Bölke, Edwin, Homey, Bernhard, Gerber, Peter Arne
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2018
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6161468/
https://ncbi.nlm.nih.gov/pubmed/30266096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40001-018-0343-8
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