Ingenol mebutate induces a tumor cell-directed inflammatory response and antimicrobial peptides thereby promoting rapid tumor destruction and wound healing

BACKGROUND: Ingenol mebutat (IM)-gel is effective for the topical treatment of epithelial tumors, including actinic keratoses (AKs) or anogenital warts (AGW). AK patients treated with IM develop intensified inflammatory reactions on sights of prior clinical visible or palpable AKs as compared to the...

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Publicado en:Eur J Med Res
Autores principales: Braun, Stephan Alexander, Baran, Julia, Schrumpf, Holger, Buhren, Bettina Alexandra, Bölke, Edwin, Homey, Bernhard, Gerber, Peter Arne
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6161468/
https://ncbi.nlm.nih.gov/pubmed/30266096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40001-018-0343-8
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