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Siplizumab, an Anti-CD2 Monoclonal Antibody, Induces a Unique Set of Immune Modulatory Effects Compared to Alemtuzumab and Rabbit Anti-Thymocyte Globulin In Vitro

Antibodies are commonly used in organ transplant induction therapy and to treat autoimmune disorders. The effects of some biologics on the human immune system remain incompletely characterized and a deeper understanding of their mechanisms of action may provide useful insights for their clinical app...

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Publicat a:Front Immunol
Autors principals: Binder, Christian, Sellberg, Felix, Cvetkovski, Filip, Berglund, Erik, Berglund, David
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686512/
https://ncbi.nlm.nih.gov/pubmed/33262770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.592553
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