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Siplizumab, an Anti-CD2 Monoclonal Antibody, Induces a Unique Set of Immune Modulatory Effects Compared to Alemtuzumab and Rabbit Anti-Thymocyte Globulin In Vitro

Antibodies are commonly used in organ transplant induction therapy and to treat autoimmune disorders. The effects of some biologics on the human immune system remain incompletely characterized and a deeper understanding of their mechanisms of action may provide useful insights for their clinical app...

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發表在:Front Immunol
Main Authors: Binder, Christian, Sellberg, Felix, Cvetkovski, Filip, Berglund, Erik, Berglund, David
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686512/
https://ncbi.nlm.nih.gov/pubmed/33262770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.592553
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