Common diseases alter the physiological age-related blood microRNA profile

Aging is a key risk factor for chronic diseases of the elderly. MicroRNAs regulate post-transcriptional gene silencing through base-pair binding on their target mRNAs. We identified nonlinear changes in age-related microRNAs by analyzing whole blood from 1334 healthy individuals. We observed a large...

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Библиографические подробности
Опубликовано в: :Nat Commun
Главные авторы: Fehlmann, Tobias, Lehallier, Benoit, Schaum, Nicholas, Hahn, Oliver, Kahraman, Mustafa, Li, Yongping, Grammes, Nadja, Geffers, Lars, Backes, Christina, Balling, Rudi, Kern, Fabian, Krüger, Rejko, Lammert, Frank, Ludwig, Nicole, Meder, Benjamin, Fromm, Bastian, Maetzler, Walter, Berg, Daniela, Brockmann, Kathrin, Deuschle, Christian, von Thaler, Anna-Katharina, Eschweiler, Gerhard W., Milman, Sofiya, Barziliai, Nir, Reichert, Matthias, Wyss-Coray, Tony, Meese, Eckart, Keller, Andreas
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686493/
https://ncbi.nlm.nih.gov/pubmed/33235214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19665-1
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