ADORA2A variation and adenosine A(1) receptor availability in the human brain with a focus on anxiety-related brain regions: modulation by ADORA1 variation

Adenosine, its interacting A(1) and A(2A) receptors, and particularly the variant rs5751876 in the A(2A) gene ADORA2A have been shown to modulate anxiety, arousal, and sleep. In a pilot positron emission tomography (PET) study in healthy male subjects, we suggested an effect of rs5751876 on in vivo...

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Udgivet i:Transl Psychiatry
Main Authors: Hohoff, Christa, Kroll, Tina, Zhao, Baoyuan, Kerkenberg, Nicole, Lang, Ilona, Schwarte, Kathrin, Elmenhorst, David, Elmenhorst, Eva-Maria, Aeschbach, Daniel, Zhang, Weiqi, Baune, Bernhard T., Neumaier, Bernd, Bauer, Andreas, Deckert, Jürgen
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686488/
https://ncbi.nlm.nih.gov/pubmed/33235193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-020-01085-w
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