Recovery sleep after extended wakefulness restores elevated A(1) adenosine receptor availability in the human brain

Adenosine and functional A(1) adenosine receptor (A(1)AR) availability are supposed to mediate sleep–wake regulation and cognitive performance. We hypothesized that cerebral A(1)AR availability after an extended wake period decreases to a well-rested state after recovery sleep. [(18)F]CPFPX positron...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Elmenhorst, David, Elmenhorst, Eva-Maria, Hennecke, Eva, Kroll, Tina, Matusch, Andreas, Aeschbach, Daniel, Bauer, Andreas
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2017
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5402442/
https://ncbi.nlm.nih.gov/pubmed/28373571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1614677114
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