Manipulation of Autophagy and Apoptosis Facilitates Intracellular Survival of Staphylococcus aureus in Human Neutrophils

Polymorphonuclear neutrophils (PMN) are critical for first line innate immune defence against Staphylococcus aureus. Mature circulating PMN maintain a short half-life ending in constitutive apoptotic cell death. This makes them unlikely candidates as a bacterial intracellular niche. However, there i...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Mulcahy, Michelle E., O’Brien, Eóin C., O’Keeffe, Kate M., Vozza, Emilio G., Leddy, Neal, McLoughlin, Rachel M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686353/
https://ncbi.nlm.nih.gov/pubmed/33262756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.565545
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