Manipulation of Autophagy and Apoptosis Facilitates Intracellular Survival of Staphylococcus aureus in Human Neutrophils

Polymorphonuclear neutrophils (PMN) are critical for first line innate immune defence against Staphylococcus aureus. Mature circulating PMN maintain a short half-life ending in constitutive apoptotic cell death. This makes them unlikely candidates as a bacterial intracellular niche. However, there i...

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Détails bibliographiques
Publié dans:Front Immunol
Auteurs principaux: Mulcahy, Michelle E., O’Brien, Eóin C., O’Keeffe, Kate M., Vozza, Emilio G., Leddy, Neal, McLoughlin, Rachel M.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020
Sujets:
Immunology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686353/
https://ncbi.nlm.nih.gov/pubmed/33262756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.565545
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